Sabyasachi Sen completed his graduation in commerce and a special B.A., followed by a diploma in journalism. Alongside his professional career in private organizations, he was also involved in home tutoring and journalism. His journey as a writer began in the early 1990s, and since 2007, he has been editing the magazine Karubasana.

A poet, essayist, and novelist, Sen has continued writing throughout his career, skillfully balancing his literary pursuits with his other professional commitments. His deep interest in avant-garde literature and the Hungry Generation movement has set his works apart from conventional literary trends. However, his role as an editor has remained inseparable from his creative endeavors.

Over the years, he has published several notable works across different genres. His poetry collections include Antyaj Andhakar (2001), Chengis-er Ghora (2007), and Muktir Prerona O Path (2013). He has also penned short story collections such as Mangs Rondonkalin Ghran (2008) and Onek Purono Shishirbhaja Golpo (2024). His novels include Hemant-er Karubasana O Parajiter Akhyan (2018).

In addition to fiction and poetry, Sen has made significant contributions to literary criticism and essays, with works such as Khomota, Sharir O Jounota (2021), Char Fyatarur Golpo (2024), and Hungry Generation Andolon (2025). His body of work continues to reflect his distinctive literary voice and intellectual engagement with contemporary and experimental literature.